Annotation: The purpose of the article is to study modern approaches to the construction of the process of updating the technical base of the enterprise, identification of the main problems associated with this process at the pharmaceutical enterprises of Ukraine. The article analyzes two different approaches to the allocation of stages of this process. Also, methods for updating the technical base of the enterprise were determined. The peculiarities of technical updating at the pharmaceutical enterprises of Ukraine are determined. The interdependence between the strategy of enterprise development and its technical policy is analyzed. General recommendations are given that will help to improve the state of the technical base of pharmaceutical and any other industrial enterprise.