Про журнал

Анотація: (English) The subject of the present research is the specificity of the prehospital management of acute life-threatening conditions of diabetic ketoacidosis (DKA) and severe neuroglycopenia in patients with type 1 diabetes mellitus (T1DM) within the framework of the American emergency medical services (EMS) system. The clinical situation is analyzed wherein the provision of urgent care under conditions of information deficit and severe time constraints becomes a catalyst for severe iatrogenic complications. In focus are the cognitive biases of providers, the phenomenon of diagnostic obfuscation and systemic contradictions between the complex transcellular biochemistry of endocrine crises and the rigid architecture of field operational algorithms. The objective of the work consists in conducting a comprehensive, pathophysiologically substantiated critical analysis of the most common diagnostic and therapeutic errors committed by emergency medical crews. The research seeks to deconstruct the mechanisms of iatrogenesis occurrence to substantiate the necessity for the profound humanization and conceptual optimization of local EMS protocols. To realize the set objective, an integrative critical review design was applied, combining elements of the retrospective analysis of clinical guidelines and the assessment of epidemiological metrics. Leading medical repositories (PubMed, Cochrane Library, Scopus) served as the information base, encompassing specialized publications for the 2010-2024 period. The research synthesizes current consensuses of US associations (ADA, NAEMSP, ACEP) and representative data of the National Emergency Medical Services Information System (NEMSIS). The extracted data array was subjected to thematic content analysis with the stratification of identified deviations into three fundamental categories: diagnostic distortions, osmotic catastrophes of fluid resuscitation and pharmacotherapeutic incidents. The research results convincingly demonstrate that the high frequency of complications in patients with T1DM is a logical consequence of systemic algorithmic dissonance rather than the individual incompetence of medical professionals. To break the vicious cycle of iatrogenesis, the mandatory integration of expanded screening (POCT) into the basic triage protocol, the categorical rejection of the prehospital application of exogenous insulin and the transition to a restrictive, physiologically calibrated tactic of infusion therapy and the gentle alleviation of hypoglycemia (D10W) are critically necessary. The global transformation of prehospital endocrinology requires the abandonment of the rigid “cookbook medicine” concept in favor of adaptive guidelines returning to paramedics the right to scientifically substantiated clinical judgment.

Анотація: (English) The article reveals the theoretical, physico-chemical, and practical aspects of the formation of resistant starch during the preparation, cooling, and reheating of starch-containing products. It has been established that the formation of resistant starch depends on the starch structure, the ratio of amylose and amylopectin, as well as on the processing conditions. Special attention is paid to retrograde modification, which occurs after heat treatment and subsequent cooling of the product, and is a key factor for the formation of resistant starch type RS3. Data on products that have the greatest potential for the formation of resistant starch are summarized, as well as its importance for metabolic health. Resistant starch helps to reduce the postprandial glycemic response, participates in fermentation in the colon, and may have a beneficial effect on the intestinal microbiota. The article discusses the potential applications of resistant starch in the field of nutrition and food technology. The main limitations were also identified, and directions for future research in this area were outlined.

Анотація: (English) At most large domestic enterprises, the HR department and the payroll department report to different managers, which creates a gap between HR decisions and their reflection in payroll calculations and increases the risks during inspections by regulatory authorities. The article examines the organizational and technological conditions under which a personnel evaluation system becomes an effective tool for enterprise management. Based on the author's management experience at three large enterprises – SE “Pivdennyi Sea Port Administration,” OilGasChem Service (OGC Service), and Lukoil Technologies Services Ukraine – a comparative analysis of personnel evaluation methods is conducted, the role of personnel commissions is characterized, and the author's HR-ERP system, implemented from scratch at two enterprises (OilGasChem Service (OGC Service) and Lukoil Technologies Services Ukraine), is described. It was found that combining a competency model, KPI approach, and performance review provides better management results than using each method separately. It was shown that combining the functions of the HR manager and the head of the payroll department in one position significantly reduces the number of calculation errors and ensures end-to-end consistency of personnel documentation and reporting. The scientific novelty is the concept of “live calculation” – an architectural solution in which any change in personnel status automatically and without delay recalculates accruals, which fundamentally distinguishes the system from standard solutions based on the paradigm of closing the calculation month.

Анотація: (English) This publication is dedicated to the quantitative evaluation and mathematical substantiation of the economic efficacy of the proprietary VFRP (Visual Finish-Result Planning) technology within the context of retail chain deployment. The study is grounded in a comprehensive analysis of a professional project portfolio spanning from 2007 to 2022, encompassing 108 completed fit-out projects (n = 108). The methodology demonstrates no statistically significant schedule deviation within the observed sample, while ensuring high operational stability during the simultaneous management of up to 17-20 assets. The author proposes an innovative management system predicated on backward scheduling mechanisms and the visualization of the target state as a “Single source of truth”. The study presents a mathematical model for the minimization of economic attrition, encompassing the formalization of empty rent expenditures, opportunity costs and rework expenses. Particular emphasis is placed on the variable frequency response mechanism, which ensures the exponential decay of temporal errors through non-linear control reinforcement at critical interaction nodes. Empirical verification across international chains confirms that the VFRP technology guarantees zero schedule variance in 95% of implementation cases. The research findings position VFRP as a fundamental investment risk hedging mechanism that ensures the stabilization of operational profit from the inaugural day of the lease.